How many injections are needed for patients receiving an epidural steroid injection? Often, symptoms are relieved, or at least reduced, with just one injection. That said, there can also be a cumulative effect of more than one injection. Therefore, patients often receive a series of two or three injections spaced apart within a few weeks, to try to minimize the inflammation in the spine.
For my practice, if a patient finds no relief of symptoms after one injection, I do not continue injecting the spine. If a patient finds complete relief of symptoms after one injection, I also stop after one injection. In patients who have partial relief of symptoms after one injection, I will often recommend a second, or even a third, injection to help maximize relief of pain.