Definition: Paget’s Disease is known as a bone remodeling disorder. Bone may seem like a very inactive tissue, but this is not the case. Bone is constantly undergoing ‘turnover’ or replacement. New bone is formed, and old bone is absorbed. This process is known as bone remodeling.
In most people this remodeling process occurs without problems. However, the process can go awry and create abnormalities of the bone. In Paget’s Disease, the bone remodeling process is disregulated. New bone is placed where it is not needed, and old bone is removed where it is needed. This disregulation can distort the normal skeletal architecture.
For more information: Paget's Disease of Bone
