Definition: The nonossifying fibroma (NOF), also called a fibrous cortical defect, is a common bone tumor usually found in children. This type of tumor is benign, therefore it is not the type of disease that will spread to other areas. However, a nonossifying fibroma can cause destruction of bone and isolated symptoms at the site of the tumor.
The most common problem that the nonossifying fibroma will cause is weakening of the bone. This may lead to increased susceptibility to fracture at that location (this type of fracture is called a pathologic fracture). Because of this, the nonossifying fibroma lesion may need to be treated in the operating room to prevent a fracture.
Also Known As: Fibrous Cortical Defect, N.O.F.
