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Readers Respond: Did You Know About Possible Side-Effects of Cortisone?

Responses: 357


Updated January 13, 2010

Cortisone Injections

I had already 3 of those injectins, never had any side effects, I was informed of possible side effects but I'm happy my pain is gone, at least for a little while about 3 months that's how long they last for me.
—Guest Lore

Some of them--still worth it.

I was told about elevated blood sugar and rare cases of irritability and headaches, but I had no idea I'd have a period that lasted nearly 2 months. I had 2 treatments and no regrets. The pain I was in beforehand was far worse than the inconvenience of 2-month spotting. I felt immediate relief.
—Guest Liz

Never again

I can only hope other woman read this and don't feel so alone,I injured my knee and after an X-ray and 30sec consult my orthodo says do you want steroid shot?i agreed hesitantly as I could barley walk on that leg hoping it would provide relief, well it took a few days then voila knee improved drastically,however the nightmare begins I have been bleeding (period bleeding) for almost two weeks straight now & I've never had abnormal periods and never over 5days with maybe 2heavy days it is showing no signs of stopping or slowing down, I am not preg or peri menopause, I finally had an epiphany, holy crap the steroid shot, sure enuff all over internet same horror stories, they sure don't warn you of this Side effect, prob won't even admit it based on stuff I've read wow...you don't realise the power of this drug until it cures your pain or wreaks havoc on your body..I'm exhausted and depressed praying this will stop and I have 10days before my gyno can see me.god help me!
—Guest Sore knee

Good So Far

I had 2 shots yesterday and already I have some relief. Was concerned this morning when my blood sugar was up and face beet red. Call to my Dr. assured me that this no doubt is from the Cortisone, and I am further assured from some letters here. Thank you, I will continue to have these in intervals as long as they work. My last injections were 9 months ago and only recently has the severe pain returned. Thanks.
—Guest norinne

What Happened?

I've had cortisone shots before, but not for several years. Had one in my knee today, and by nightfall I thought my head was going to explode! The headache was just horrific, and I spent most of the night just wandering around the house unable to sleep. Dr. asked if I was allergic to anything, but didn't warn me about the headache. Don't think I'll do this again!!
—Guest Duffersmom

shot in wrist

had an injection in wrist on Wednesday was not told of side effects did not sign any consent form and my tendon is now ruptured and can't move my thumb now have to have op to repair the ruptured tendon, not happy bunny
—Guest Claire

I felt crazy

Hi Julie, I am getting the cortisone shots in both my knees because of arthritis. My doctor just told me that it would raise my blood sugar high if I tested right away, so I never do. I am just trying to avoid having knee replacement surgery, so am willing to put up with all the strange reactions after the shots......both good and bad. So glad that I can find out more information from people like you, so thank you for your information about the shots.
—Guest Julie


I have been getting my knees injected for years. No problems. Recently I had 2 injections in my back and hips. The pain is gone which is great but now I can't sleep, constantly flushing or having chills. Depressed, restless,can't focus. Feel like crying alot. This is not normal for me. don't know if I would go through this again. Now that I am out of pain I feel like I am going through menopause again. It's awful.
—Guest donna.orth@yahoo.com

Always know the risks

I am familiar with the problems Not Informed mentions above with messed up menses as that has happened to me and took three months to straighten out. My prior steroid shot was when I was under anesthesia so thought some of my symptoms were from the anesthesia not the steroid. My second shot was yesterday and I am extremely thirsty,my head is foggy, and I have heartburn.
—Guest Karen

side effects

I have had two shots in my knee 1 3/4 years apart, one in my ankle, one in my thumb (three years painfree) and recently in my hip. Never had 1 side effect. I am very lucky as it really helps.
—Guest Laura


I have had arthritis in my knees for a long time. I have had several injections. Some worked well, and some not so well. I just had 3 more shots 1 week apart due to another torn meniscus. I have never had any problems or side effects. I would have the shot again in a heartbeat.
—Guest joyce

Not aware of post menopausal bleeding

I probably would have gone ahead and had the shot for my golfer's elbow, as I had already had two others after menopause. However, I will not ever have another shot unless it is absolutely critical! Some doctors will not believe that cortisone shots cause this but I endured both an exam from by Gynecologist, who also requested that I do a saline-sonogram (SIS). This wasn't a horrible procedure. Having a mini-period was so scary! The sonogram revealed no abnormalities. I will likely have to pay for the bulk of the test because I have a high insurance deductible. I am so thankful on the one hand for the pain relief in my elbow, but now am very sad as to what I had to endure afterwards and the realization that I may never be able to have this shot again. There is not a great deal of information on the web about this issue as it is considered 'anecdotal' but it is there if you dig.

totally worth the pain

I had my second cortisone shot today on my L4 L5. Hurt like no other!! But I know I am on the mend. Was fully aware of the side affects because like some people on here that can't ask questions or look on the internet... I did. People! Stop blaming the doctors ! They do wanderful things and are here to helps us. I have yet to hear of a doctor that would cause intensional pain and side effects. I to aggree with "your mamma" stop blaming.g these doctors and take responsability ... I say well done to my doctor and his nurses. Because of what they have done for me I can now have a life with my beautiful children . I can do things that I yacht been able to do for 3 years.. well done doc!!!
—Guest jut


I have Dequervain's tendinitis and time ice physical therapy and topical steroids have provided a few minutes of relief at best. I got my first cortisone injection three days ago, the injection was very painful and at first the pain in my wrist was worse if anything. That night I experienced hot flashes and nausea. This morning I woke up virtually pain free for the first time in months. The side affects were completely worth it.
—Guest jack rva

Not worth it

I had a cortisone shot in my shoulder a few years ago... While the shot wasn't too painful for me, my shoulder was afterwards. It never really took the pain away, and also started my period which lasted for a month straight! I got scared so I booked an appointment with my gyno. I was told the shot is what did it! I didn't have enough sense to ask about the side effects, but I learned my lesson and always ask about everything now. Needless to say, I will never get another cortisone shot.
—Guest Ash
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  6. Injections
  7. Side-Effects of Cortisone Shots - Your Experience With a Cortisone Shot

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