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Readers Respond: Did You Know About Possible Side-Effects of Cortisone?

Responses: 357


Updated January 13, 2010

Had Bad headache for more than 48hrs

Ive gotten a cortisone shot on my left knee for arthritis by a recognized orthopedic surgeon three days ago, I forgotten to ask about side effects, but as soon as I got home the side effect showed with a tremendous headache, he's a vast expierienced surgeon but my instructions were to take acetaminophen after the local anesthetic wore off, hope it will go away.
—Guest Tanya Rosario Frank

very painfull

I have had two shots of cortisone today, one each in the base of the thumbs. The actual shots were quite painfull, but nothing to the pain I am now experiencing four hours later, now the local has worn off. I can only hope that the co-codamol I am taking for relief will kick in sooner rather than later. As for long term effects and success, I cannot comment as it is very early days. I will update as time goes on.
—Guest richie


No, I had an injection for a morton's neuroma between my second and third toe of my left foot. It was put in the nerve instead of the interspace and it caused me to get a hammer toe (my second toe). I don't think the doctor knew what she was doing. I will never go back to her.
—Guest guest no

Not was told of Side Effects

I was not told that the injections would cause my blood pressure to go so high! my B/P runs 110/68 after injection the next day its 160/88
—Guest No I would not have taken the injections


i had a steroid inject. into my shoulder yesterday for rheumatoid arthritis, this is the third one in a year, 2 injections were inserted into the front of the shoulder and i have noticed indentations (loss of fat) there, i asked yesterday for it to be put into the back of shoulder, the first 2 shots were given by a nurse and the one yesterday by a doctor, i have since read that the reason for the indentations is that the jabs were put into the fat in my shoulder instead of the muscle, so for anyone getting these injections i would advise them to get it done by someone who knows what they are doing. A few years ago i also experienced some bleeding, my doctor sent me to a gynocologist as she thought it could be ovarian or cervical cancer, i was really worried but they found nothing wrong, again i discovered that steroids can do this, so if you have bleeding please bear in mind it could be the steroid and not anything more sinister.
—Guest hi

Injection in the Palm

Carpal tunnel in right wrist. Yesterday got the shot. Was not told of any side effects. I have had a headache for 24 hours and nothing I take gets rid of it. I hope it will wear off in a couple of days. Hopfully the carpal tunnel improves in a week or 2. Was glad to hear of this site to know what side effects could be. I think it depends on the Dr whether the Shot works well or not. They need to shoot for the right spot. I think I have a experienced doctor. Might be a good thing to ask around for a good doctor who does this procedure. I went out of town for my Dr. My family Dr recomended him.
—Guest Guest Mary

First Injection - Working Well

I went to the orthopaedist w/intense knee pain - thought it had been dislocated. Turns out it's a Baker's Cyst, and a cortisone shot was suggested. Had it yesterday, started feeling relief in 2-3 hrs, slept well, and am having a good day today. BUT, I did "feel funny" shortly after the injection, fainted, and promptly recovered in about 5-10 mins. Small price to pay for so much relief.
—Guest GuestIrene

Would Definitely Do It Again

Last week, I had a cortisone shot in my left knee in order to hopefully alleviate the severe pain that I was having because of severe arthritis. It was the best decision that I have ever made because after the shot, I did have the steroid flare that everyone here is talking about, i.e. the painful knee to the point of where I wanted to cry, but after the pain wore off, my knee felt better than it has in a long time. Also, today, I had a second injection in my right knee and I am now experiencing steroid flare but it is not too bad. I am sure that my experience is different than most others because I was lucky enough to find a great orthopedic doctor who took the time to explain to me what side effects to expect and how to deal with them. Thank you, Dr. Saslow, for allowing me to walk normally for the first time in a long time.
—Guest Yes

Cortisone for Plantars Faciatas

I was not give any of the side effects of cortisone from my extremely busy doctor. I had shots into both of my feet that were extremely painful but the pain went away fairly quickly. My feet this mornig for the first time in two years were achey but much better then they have been. Some of my side effects were Nervousness, Severe headache, Nauseous & last night I had severe hot flashes ( but I am in menopaus). I am going to see how long the side effests go on & how long my feet feel better before I go for another.....
—Guest No

Considering this

I'm an RN and also a dancer. A few weeks ago, I gave myself plantar fasciitis during a strenuous class and the doctor recommended rest, ice, support, Vitamin B12 and cortisone shots as a next phase. We're at the next phase. What really gets me are all these folks blaming the docs for not giving them the side effects....why didn't you take responsibility and become part of your own health-care team? Why did you look up the side effects AFTER the fact? Yes, we're supposed to educate you, but with only 15-20 minutes allowed by your insurance, you have to do your part too. I'm sorry some of you had problems; but next time, go into the procedure well-informed and make a fully informed decision because YOU took control of YOUR health! I'm going ahead with these shots after spending awhile online looking stuff up tonight. I know the risks, have my questions for my doctor and can make the decision best for me based on my reading and research. It's not hard, just DO it!
—Guest ahenra


I'm glad I didn't read these comments before I had my first injection five years ago, or I would have been too frightened to have it. Fortunately for me, I had none of the negative reactions mentioned here. I was immediately pain-free for the first time in 3 years, and the first shot lasted more than 3 months. I got a second one that lasted less than a month, and a third one in the hope that the short-lived second one was a fluke - it wasn't. I had my left hip replaced in 2007 (at age 53). I was aware that I had arthritis in my right hip, but really had no serious symptoms until fall 2010. Had my first injection in the right hip a month ago; again, it was wonderful to be able to put my pants on standing up, to walk at normal speed, to tie my shoes, and to squat and get up! But it only lasted about 3 weeks, and my limitations have all returned. I won't have surgery for at least a year, so ... glad summer is coming and I'll be able to get in the pool for some exercise!
—Guest Not all of them -

Feel like a new person

Received an injection March 2011 for a tear in my rotator cuff. By the time I left the Dr. office and home (20 minutes) the pain was almost gone. It took a couple of days and I was pain free, sleeping thru the night, being able to lift my arm etc. pain free. I just finished physical therapy and I feel wonderful. I have no hesitation regarding these injections, they don't heal but give me relief to be able to live normally. I did have bruising at the site & a slight tenderness which was nothing compared to the pain I had. Of course, no heavy lifting etc.. Also, I have a wonderful doctor.
—Guest Pat

Never Again

I am 26 and I recently had cortisone injection into my lumbar spine. I was only told about pain and redness at the injection site and increased pain for about a week. Not only did the shot not work at all, but the side effects are simply awful. Even if the shot had worked, these side effects would not have been worth it. I also can't find anything about when they will stop. Not only was I never told this could be a side effect, I never found it listed as a possible side effect when doing research. I'm extremely upset and frustrated. There is no way I would have done this if I'd known. NEVER AGAIN!
—Guest Kelly

Had two looking at the third

Knew about some side effects but had none with either injection. I have had hip arthritis for three years have had two injections and been free from pain for three years until twodays ago when i lifted something wrong.
—Guest Don


  1. About.com
  2. Health
  3. Orthopedics
  4. Arthritis
  5. Arthritis Treatment
  6. Injections
  7. Side-Effects of Cortisone Shots - Your Experience With a Cortisone Shot

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