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Readers Respond: Did You Know About Possible Side-Effects of Cortisone?

Responses: 357


Updated January 13, 2010


had the shot in my elbow today, was told it would hurt for a couple of days, not informed of any other side effects, it felt as though the needle went into my bone and was extremely painful, have not been able to use my arm all day as pain is greatly increased, don't think i will be doing it again.
—Guest karen Phillips


I had my first shot on Friday. I studied the effects and after effects and felt comfortable going for it. I've been in severe pain for the past few years from a broken upper arm that didn't heal properly and hence, caused what the doctor calls "severe athritis" in my shoulder. I've lost any significant range of motion and can't even hold a newspaper without pain. I had the shot on Friday and today (Sunday) I was able to read and hold the paper without pain and I'm looking forward to changing my sheets without help (although my neighbor advises not to do anything strenuous for a few days). No side effects but, since I can sleep without being woken every half hour with pain, have been sleeping most of the past few days.

cortisone in knee for arthritis

Had the injection yesterday. No adverse effects. First time in over 15 years I can walk, not crawl upstairs and am almost pain free. Have had same results when I had cortisone for heel spurs 20 years ago which never recurred. For many years needed the medro packs as a last resort for acute allergies which always provided relief in 24 hours with never any side effects. After years of suffering finally was given this miracle drug. Never occurred to me to ask for it for my advanced knee arthritis plus spurs and when my Dr mentioned it yesterday I knew I could tolerate it and hoped for minimal relief. The relief I have is absolutely miraculious and I would certainly recommend others to give it a try before going into surgery (for which I was a candidate).
—Guest Lee


Does anyone think it might be possible that because some people have a positive response and others a negative, that it is possible that some doctors have better skills at injecting cortizone than others. I had 1st for heel spurs & positive results; again for trigger finger shot hurt very bad but helped; 2 weeks ago for reinjure of rotator cuff and having terrible pain. Injection produced a flushed face and relief from pain over complete body--thought it was from old age, 68, but found that I must have arthritis. I've been a new person and pain free. Never felt better, at least for the past 10 years.
—Guest Sandra Vance

Did not know side effects

I had two injections yesterday, and glad for this site, as see my side effects are normal...flushed face, fluctuating body temp from hot flashes to chills, nausea and nervousness. I can live with these, as my pain is a lot better for rotator cuff situation and trigger finger.
—Guest 75 year old

Never do it again!

I had been in great pain for 2mos with tennis elbow. Told my doctor & he suggested getting a cortizone shot. I wasn't told about any of the possible side-effects. First I received a white spot the size of a 50cent piece; next I lost the fatty tissue & now I have weird intention; now have bruising & blood spots that show up if anything touches the area (skin thinning/ & this is after a year. Now I look like I have a deformed injured elbow. Pain is now coming back, but stayed away for 10months. Never do it again!
—Guest pat

cortisone shots in the knees

Been having problems with my knees.got to the point where i couldn' walk.& i was in alot of pain.my dr. told me about the shots,i didn't even think about it.He gave me one in each knee.woke up this morming with every little pain & i told walk .i so gald to have agreeded to get the shots. & no they didn't hurt!!!
—Guest victoria

Absolutely, YES YES

I had a epidural cortisone shot in my L4 5 and s1 48 hours ago. The shot did not hurt, my hips hurt briefly after the injection. I did not get any side effects save for soreness at the injection site for 48 hours. Just rested and feel like a brand new person now. Get educated, dont be scared to do it, Just don't overdo yourself. Hope this lasts awhile and good luck to all.

steriod flare

I had my second shot in my back and when I got home I was numb between my legs and butt. When the numbness went away it was replaced with great pain. I was told this was a reaction called steriod flare. Today is second day and pain is subsiding.
—Guest Donna

Cortisone Knee Injection

With these post, I am really baffled about the knowledge that the patients have about side affects. I had a cortisone injection in my knee yesterday. I was very leary about getting this myself, but I did not jump into right away, for I do not take needles well, actually pass out on any needle injection (mind games). It was not to bad when injected (did not pass out) with needle. I felt little discomfort in the spot of the injection for a couple of hours. I woke up the next morning and was relieved of pain to the point I did not need my crutch to walk. Just a little history on my knee, April 12, 2010 I had knee surgery (Mckay procedure) which took awhile to recover from after 8 months. Then I tore my minicus and had surgery again on April 4th, 2011 its been a couple of weeks now while going through theory for rehab I can not get the swelling to go down and petela pain. I was told about shot, went home researched side affects of cortisone shot, then went back to doctor to get shot.
—Guest Greg

Yes, Absolutely!!!

Have screws & plates from calcaneal fracture from a car accident. Had severe front/top of foot pain for 4 years, often limped & exercise aggravated it. The podiatrist said diagnosed very severe arthritis in the top of my foot & suggested a steroid injection to help with inflammation. Felt some pressure & slight ache during the injection. I was told of possible discomfort in the day or two after & yes, I experienced that. No discoloration. No other side effect. Best of all -- no current pain. I am able to walk better & am much more comfortable every day and can exercise again. I'm hoping the relief will last a long time -- yes, very worth the minor discomfort -- wish I had tried it long before I finally did.
—Guest Sharon


I've had shots in 3 different areas; shoulder and both sides of my back for sciatic nerve pain. The only side effects I've had are moderate to severe cramps mainly in my left leg and foot. That is the side most of my pain is on in my back. I rather deal with the cramps than the pain when it is so bad you get nausea, chills and shakes. Only problem is the shot last 4 months at the most for me.
—Guest Fanniemae

Had me worried until I read this site

I've had 2 cortisone injections in the hips. One was 3 yrs ago in the Right hip which lasted about 3 1/2 months. Had no reactions afterwards, I felt like a million bucks!! Yesterday I went for a cortisone injection in the Left hip. Got off the table and began to cry because I was pain free again. However, after I got home about 3 hours after the shot, my head began to hurt, felt "odd", anxious, and couldn't sleep last night. Woke up at 1am with my heart racing and facial flushing, I thought I was going to have a heart attack! 24 hrs later, my headache is still here, fascial flushing is to, don't really have an appetite, feel drowsy. Called PCP to see if there is anything I can take to ease these symptoms, waiting for the callback. Would I do it again, not sure, I guess it depends on how long I will feel like this. I can deal with the fascial flushing, but this headache is driving me crazy! I am comforted to see similar reactions to this injection because I was getting worrie
—Guest Jeanette


Had knee surgery n Feb. B n hard headed does make a soft behind. Took brace of way to sound reinjured my knee. Got injection to day doctor was great didnt hurt a not one bit. Did get a touch of sum side effects,but ALL medications have sum side effects. My doctor did explain and watched me for a while at the office until i felt comfortable to leave. I am a very active mother of 3. Age 38 under the same good doctors care i will get another injection. My advice choose the right doctor and makes a whole world of difference!! Thanks Dr. F. Vakili
—Guest stickers

Second one today

Had both knees injected a year ago and had great results for a while. I did have the "cortisone flare" in one knee the first time, and it was agonizing. I hoped it wouldn't happen again, but it did in the same knee. Other knee is just slightly sore. The "flare" went away last time in a day or so, and I enjoyed noticeably improved knee symptoms from the injections. The injections were no worse than getting novacaine at the dentist's office. What's great about the lidocaine they mix with the cortisone is that when you get home, you're symptom free -- like before your knees ever hurt in the first place. That was wonderful, even if only short-lived. I would definitely do this again. My orthopedist says it's safe for the tenons and cartilage if not repeated too frequently. I went a year between injections.
—Guest Larry Shushan
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  4. Arthritis
  5. Arthritis Treatment
  6. Injections
  7. Side-Effects of Cortisone Shots - Your Experience With a Cortisone Shot

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